Distinguish between temporal and spatial summation.
In temporal summation the postsynaptic neuron is fired by a single synaptic knob. Although a single
firing of the presynaptic knob does not release enough transmitter to fire the apposing neuron, if the knob
is fired repeatedly in a short enough time span, the released neurotransmitter may reach sufficient levels
to induce the apposing neuron to fire.
In spatial summation, the neurotransmitter required to fire the apposing neuron is accumulated not
by one knob releasing the neurotransmitter many times over a short period of time, but by the one-time
effort of many knobs simultaneously releasing their small amount of neurotransmitter.
In temporal summation the postsynaptic neuron is fired by a single synaptic knob. Although a single
firing of the presynaptic knob does not release enough transmitter to fire the apposing neuron, if the knob
is fired repeatedly in a short enough time span, the released neurotransmitter may reach sufficient levels
to induce the apposing neuron to fire.
In spatial summation, the neurotransmitter required to fire the apposing neuron is accumulated not
by one knob releasing the neurotransmitter many times over a short period of time, but by the one-time
effort of many knobs simultaneously releasing their small amount of neurotransmitter.
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